Prof. Dr. ID: 65683

Boris Fehse

graph of relations

Publications

  1. 2019
  2. Nanobody-targeting of epidermal growth factor receptor (EGFR) ectodomain variants overcomes resistance to therapeutic EGFR antibodies

    Tintelnot, J., Baum, N., Schultheiss, C., Braig, F., Trentmann, M., Finter, J., Fumey, W., Bannas, P., Fehse, B., Riecken, K., Schütze, K., Bokemeyer, C., Rösner, T., Valerius, T., Peipp, M., Koch-Nolte, F. & Binder, M., 04.2019, In : MOL CANCER THER. 18, 4, p. 823-833 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  3. Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo

    Giersch, K., Bhadra, O. D., Volz, T., Allweiss, L., Riecken, K., Fehse, B., Lohse, A. W., Petersen, J., Sureau, C., Urban, S., Dandri, M. & Lütgehetmann, M., 01.2019, In : GUT. 68, 1, p. 150-157 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  4. Cancer Suicide Gene Therapy with TK.007

    Hossain, J. A., Riecken, K., Miletic, H. & Fehse, B., 2019, In : Methods Mol Biol. 1895, p. 11-26 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  5. Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours

    Ricklefs, F. L., Maire, C. L., Reimer, R., Dührsen, L., Kolbe, K., Holz, M., Schneider, E., Rissiek, A., Babayan, A., Hille, C., Pantel, K., Krasemann, S., Glatzel, M., Heiland, D. H., Flitsch, J., Martens, T., Schmidt, N. O., Peine, S., Breakefield, X. O., Lawler, S., Chiocca, E. A., Fehse, B., Giebel, B., Görgens, A., Westphal, M. & Lamszus, K., 2019, In : Journal of extracellular vesicles. 8, 1, p. 1588555

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  6. 2018
  7. Transient Retrovirus-Based CRISPR/Cas9 All-in-One Particles for Efficient, Targeted Gene Knockout

    Knopp, Y., Geis, F. K., Heckl, D., Horn, S., Neumann, T., Kuehle, J., Meyer, J., Fehse, B., Baum, C., Morgan, M., Meyer, J., Schambach, A. & Galla, M., 07.12.2018, In : MOL THER-NUCL ACIDS. 13, p. 256-274 19 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  8. Consensus Statement of European Societies of Gene and Cell Therapy on the Reported Birth of Genome-Edited Babies in China

    Büning, H., Griesenbach, U., Fehse, B., Ylä-Herttuala, S., Anagnou, N. P., van Beusechem, V., Raya, A. & Verhoeyen, E., 12.2018, In : HUM GENE THER. 29, 12, p. 1337–1338 2 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Transfer

  9. Cellular Barcoding Identifies Clonal Substitution as a Hallmark of Local Recurrence in a Surgical Model of Head and Neck Squamous Cell Carcinoma

    Roh, V., Abramowski, P., Hiou-Feige, A., Cornils, K., Rivals, J-P., Zougman, A., Aranyossy, T., Thielecke, L., Truan, Z., Mermod, M., Monnier, Y., Prassolov, V., Glauche, I., Nowrouzi, A., Abdollahi, A., Fehse, B., Simon, C. & Tolstonog, G. V., 20.11.2018, In : CELL REP. 25, 8, p. 2208-2222.e7

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  10. Clonal dynamics studied in cultured induced pluripotent stem cells reveal major growth imbalances within a few weeks

    Brenière-Letuffe, D., Domke-Shibamiya, A., Hansen, A., Eschenhagen, T., Fehse, B., Riecken, K. & Stenzig, J., 18.06.2018, In : STEM CELL RES THER. 9, 1, p. 165

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  11. The phosphotyrosine phosphatase SHP2 promotes anergy in chronic lymphocytic leukemia

    Schliffke, S., Buhs, S., Bolz, S., Gerull, H., von Wenserski, L., Riecken, K., Fehse, B., Nollau, P. & Binder, M., 12.04.2018, In : BLOOD. 131, 15, p. 1755-1758 4 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  12. Locally Ablative Radiation Therapy of a Primary Human Small Cell Lung Cancer Tumor Decreases the Number of Spontaneous Metastases in Two Xenograft Models

    Frenzel, T., Siekmann, J., Grohmann, C., Valentiner, U., Schmitz, R., Riecken, K., Fehse, B., Schumacher, U., Lange, T. & Krüll, A., 15.03.2018, In : INT J RADIAT ONCOL. 100, 4, p. 1044-1056 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  13. The Time Is Ripe for Somatic Genome Editing: NIH Program to Strengthen Translation

    Fehse, B. & Abramowski-Mock, U., 07.03.2018, In : MOL THER. 26, 3, p. 671-674 4 p.

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  14. Efficient gene editing via non-viral delivery of CRISPR-Cas9 system using polymeric and hybrid microcarriers

    Timin, A. S., Muslimov, A. R., Lepik, K. V., Epifanovskaya, O. S., Shakirova, A. I., Mock, U., Riecken, K., Okilova, M. V., Sergeev, V. S., Afanasyev, B. V., Fehse, B. & Sukhorukov, G. B., 01.2018, In : NANOMED-NANOTECHNOL. 14, 1, p. 97-108 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  15. High bone turnover in mice carrying a pathogenic Notch2-mutation causing Hajdu-Cheney syndrome

    Vollersen, N., Hermans-Borgmeyer, I., Cornils, K., Fehse, B., Rolvien, T., Triviai, I., Jeschke, A., Oheim, R., Amling, M., Schinke, T. & Yorgan, T. A., 01.2018, In : J BONE MINER RES. 33, 1, p. 70-83 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  16. Genomeditierung durch CRISPR und Co

    Fehse, B., 2018, Stammzellforschung: Aktuelle wissenschaftliche und gesellschaftliche Entwicklungen. Zenke, M., Marx-Stölting, L. & Schickl, H. (eds.). 1 ed. Baden-Baden: Nomos, p. 97-114 18 p. 4. (Forschungsberichte der interdisziplinären Arbeitsgruppen der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 39).

    Research output: SCORING: Book or contribution to book/anthologySCORING: Contributions to collected editions/anthologiesTransfer

  17. „Rote Gentechnologie“ – Nachhaltiges Comeback der Gentherapie?!

    Fehse, B., 2018, Vierter Gentechnologiebericht : Bilanzierung einer Hochtechnologie. Hucho, F., Diekämper, J., Fangerau, H., Fehse, B., Hampel, J., Köchy, K., Könninger, S., Marx-Stölting, L., Müller-Röber, B., Reich, J., Schickl, H., Taupitz, J., Walter, J., Zenke, M. & Korte, M. (eds.). 1 ed. Baden-Baden: Nomos Verlagsgesellschaft, p. 210-214 5 p. (Forschungsberichte der Berlin-Brandenburgischen Akademie der Wissenschaften; vol. 40).

    Research output: SCORING: Book or contribution to book/anthologySCORING: Contributions to collected editions/anthologiesTransfer

  18. 2017
  19. Multi-color RGB marking enables clonality assessment of liver tumors in a murine xenograft model

    Thomaschewski, M., Riecken, K., Unrau, L., Volz, T., Cornils, K., Ittrich, H., Heim, D., Wege, H., Akgün, E., Lütgehetmann, M., Dieckhoff, J., Köpke, M., Dandri, M., Benten, D. & Fehse, B., 29.12.2017, In : ONCOTARGET. 8, 70, p. 115582-115595 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  20. Impact of molecular residual disease post allografting in myelofibrosis patients

    Wolschke, C., Badbaran, A., Zabelina, T., Christopeit, M., Ayuketang, F. A., Triviai, I., Zander, A., Alchalby, H., Bacher, U., Fehse, B. & Kröger, N-M., 11.2017, In : BONE MARROW TRANSPL. 52, 11, p. 1526-1529

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  21. SHIP1, but not an AML-derived SHIP1 mutant, suppresses myeloid leukemia growth in a xenotransplantation mouse model

    Täger, M., Horn, S., Latuske, E., Ehm, P., Schaks, M., Nalaskowski, M., Fehse, B., Fiedler, W., Stocking, C., Wellbrock, J. & Jücker, M., 11.2017, In : GENE THER. 24, 11, p. 749-753 5 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  22. Gene and Cell Therapy in Germany

    von Kalle, C., Fehse, B. & Büning, H., 10.2017, In : HUM GENE THER. 28, 10, p. 781

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  23. Genetic barcodes facilitate competitive clonal analyses in vivo

    Aranyossy, T., Thielecke, L., Glauche, I., Fehse, B. & Cornils, K., 10.2017, In : HUM GENE THER. 28, 10, p. 926-937

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  24. Clonal competition in BcrAbl-driven leukemia: how transplantations can accelerate clonal conversion

    Cornils, K., Thielecke, L., Winkelmann, D., Aranyossy, T., Lesche, M., Dahl, A., Roeder, I., Fehse, B. & Glauche, I., 14.07.2017, In : MOL CANCER. 16, 1, p. 120

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  25. IL-33-Mediated Expansion of Type 2 Innate Lymphoid Cells Protects from Progressive Glomerulosclerosis

    Riedel, J-H., Becker, M., Kopp, K., Düster, M., Brix, S. R., Meyer-Schwesinger, C., Kluth, L. A., Gnirck, A-C., Attar, M., Krohn, S., Fehse, B., Stahl, R. A. K., Panzer, U. & Turner, J-E., 07.2017, In : J AM SOC NEPHROL. 28, 7, p. 2068-2080

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  26. Impact of Molecular Genetics on Outcome in Myelofibrosis Patients after Allogeneic Stem Cell Transplantation

    Kröger, N., Panagiota, V., Badbaran, A., Zabelina, T., Triviai, I., Araujo Cruz, M. M., Shahswar, R., Ayuketang, F. A., Gehlhaar, M., Wolschke, C., Bollin, R., Walter, C., Dugas, M., Wiehlmann, L., Lehmann, U., Koenecke, C., Chaturvedi, A., Alchalby, H., Stadler, M., Eder, M., Christopeit, M., Göhring, G., Koenigsmann, M., Schlegelberger, B., Kreipe, H-H., Ganser, A., Stocking, C., Fehse, B., Thol, F. & Heuser, M., 07.2017, In : BIOL BLOOD MARROW TR. 23, 7, p. 1095-1101

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  27. Limitations and challenges of genetic barcode quantification

    Thielecke, L., Aranyossy, T., Dahl, A., Tiwari, R., Roeder, I., Geiger, H., Fehse, B., Glauche, I. & Cornils, K., 03.03.2017, In : SCI REP-UK. 7, p. 43249

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  28. Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-KPolymorphism

    Braig, F., Kriegs, M., Voigtlaender, M., Habel, B., Grob, T., Biskup, K., Blanchard, V., Sack, M., Thalhammer, A., Ben Batalla, I., Braren, I., Laban, S., Danielczyk, A., Goletz, S., Jakubowicz, E., Märkl, B., Trepel, M., Knecht, R., Riecken, K., Fehse, B., Loges, S., Bokemeyer, C. & Binder, M., 01.03.2017, In : CANCER RES. 77, 5, p. 1188-1199 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  29. Optical Barcoding for Single-Clone Tracking to Study Tumor Heterogeneity

    Mohme, M., Maire, C. L., Riecken, K., Zapf, S., Aranyossy, T., Westphal, M., Lamszus, K. & Fehse, B., 01.03.2017, In : MOL THER. 25, 3, p. 621-633

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  30. Mesenchymal stem cells engineering: microcapsules assisted gene transfection and magnetic cell separation.

    Muslimov, A. R., Timin, A. S., Petrova, AV., Epifanovskaya, O. S., Shakirova, A. I., Lepik, K. V., Gorshkov, A., Il’inskaja, EV., Vasin, A. V., Afanasyev, B. V., Fehse, B. & Sukhorukov, G. B., 2017, In : ACS BIOMATER SCI ENG. 3, 10, p. 2314-2324

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  31. 2016
  32. Генная терапия на основе трансплантации гемопоэтичеcких стволовых клеток с использованием сайт-специфического редактирования генома

    Lepik, K. V., Popova, M. O., Shakirova, A. I. S., Sergeev, V. S., Potter, A. Y., Barkhatov, I. M., Fehse, B. & Afanasyev, B. V., 11.2016, In : Genes & Cells (гены & клетки) . XI, 2, p. 21-31

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  33. Достижения в разработке инструментов для редактирования генома.

    Fehse, B., 11.2016, АЛЬМАНАХ 2016: РЕДАКТИРОВАНИЕ ГЕНОМА И ВОЗМОЖНОСТИ ГЕННОЙ ТЕРАПИИ В ОНКОЛОГИИ. 1 ed. Moskau, 4 p. 1

    Research output: SCORING: Book or contribution to book/anthologySCORING: Contributions to collected editions/anthologiesTransfer

  34. Potent in vitro and in vivo effects of polyclonal anti-human-myeloma globulins

    Schieferdecker, A., Shoshani, O., Westner, B., Zipori, D., Fehse, B., Kröger, N. & Ayuketang, F. A., 11.10.2016, In : ONCOTARGET. 7, 41, p. 67061-67070

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  35. Similar outcome of calreticulin type I and calreticulin type II mutations following RIC allogeneic haematopoietic stem cell transplantation for myelofibrosis

    Christopeit, M., Badbaran, A., Zabelina, T., Zeck, G., Fehse, B., Ayuketang, F. A., Wolschke, C. & Kröger, N-M., 10.2016, In : BONE MARROW TRANSPL. 51, 10, p. 1391-1393 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  36. Lentiviral HSV-Tk.007-mediated suicide gene therapy is not toxic for normal brain cells

    Hossain, J. A., Ystaas, L. R., Mrdalj, J., Välk, K., Riecken, K., Fehse, B., Bjerkvig, R., Grønli, J. & Miletic, H., 09.2016, In : J GENE MED. 18, 9, p. 234-43 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  37. Mesenchymal Stromal/Stem Cells Do Not Ameliorate Experimental Autoimmune Encephalomyelitis and Are Not Detectable in the Central Nervous System of Transplanted Mice

    Abramowski, P., Krasemann, S., Ernst, T., Lange, C., Ittrich, H., Schweizer, M., Zander, A. R., Martin, R. & Fehse, B., 01.08.2016, In : STEM CELLS DEV. 25, 15, p. 1134-48

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  38. Long-term in vivo single-cell tracking reveals the switch of migration patterns in adult-born juxtaglomerular cells of the mouse olfactory bulb

    Liang, Y., Li, K., Riecken, K., Maslyukov, A., Gomez-Nicola, D., Kovalchuk, Y., Fehse, B. & Garaschuk, O., 07.2016, In : CELL RES. 26, 7, p. 805-21 17 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  39. Microglia regulate hippocampal neurogenesis during chronic neurodegeneration

    De Lucia, C., Rinchon, A., Olmos-Alonso, A., Riecken, K., Fehse, B., Boche, D., Perry, V. H. & Gomez-Nicola, D., 07.2016, In : BRAIN BEHAV IMMUN. 55, p. 179-190

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  40. Digital-PCR assay for screening and quantitative monitoring of calreticulin (CALR) type-2 positive patients with myelofibrosis following allogeneic stem cell transplantation

    Badbaran, A., Fehse, B., Christopeit, M., Aranyossy, T., Ayuketang, F. A., Wolschke, C. & Kröger, N., 06.2016, In : BONE MARROW TRANSPL. 51, 6, p. 872-3

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

  41. Massive Clonal Selection and Transiently Contributing Clones During Expansion of Mesenchymal Stem Cell Cultures Revealed by Lentiviral RGB-Barcode Technology

    Selich, A., Daudert, J., Hass, R., Philipp, F., von Kaisenberg, C., Paul, G., Cornils, K., Fehse, B., Rittinghausen, S., Schambach, A. & Rothe, M., 05.2016, In : STEM CELL TRANSL MED. 5, 5, p. 591-601 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  42. Primary Human Hepatocytes Repopulate Livers of Mice After In Vitro Culturing and Lentiviral-Mediated Gene Transfer

    Bierwolf, J., Volz, T., Lütgehetmann, M., Allweiss, L., Riecken, K., Warlich, M., Fehse, B., Kalff, J. C., Dandri-Petersen, M. & Pollok, J-M., 05.2016, In : TISSUE ENG. 22, 9-10, p. 742-53 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  43. Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes

    Labenski, V., Suerth, J. D., Barczak, E., Heckl, D., Levy, C., Bernadin, O., Charpentier, E., Williams, D. A., Fehse, B., Verhoeyen, E. & Schambach, A., 26.04.2016, In : BIOMATERIALS. 97, p. 97-109 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  44. Investigation of the Mesenchymal Stem Cell Compartment by Means of a Lentiviral Barcode Library

    Bigildeev, A. E., Cornils, K., Aranyossy, T., Sats, N. V., Petinati, N. A., Shipounova, I. N., Surin, V. L., Pshenichnikova, O. S., Riecken, K., Fehse, B. & Drize, N. I., 04.2016, In : BIOCHEMISTRY (MOSC). 81, 4, p. 373-81 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  45. Digital PCR to assess gene-editing frequencies (GEF-dPCR) mediated by designer nucleases

    Mock, U., Hauber, I. & Fehse, B., 03.2016, In : NAT PROTOC. 11, 3, p. 598-615 18 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  46. Digital PCR Panel for Sensitive Hematopoietic Chimerism Quantification after Allogeneic Stem Cell Transplantation

    Stahl, T., Rothe, C., Böhme, M. U., Kohl, A., Kröger, N. & Fehse, B., 2016, In : INT J MOL SCI. 17, 9, p. E1515

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  47. 2015
  48. Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I

    Kühn, S. C., Koehne, T., Cornils, K., Markmann, S., Riedel, C., Pestka, J. M., Schweizer, M., Baldauf, C., Yorgan, T. A., Krause, M., Keller, J., Neven, M., Breyer, S., Stücker, R., Muschol, N., Busse, B., Braulke, T., Fehse, B., Amling, M. & Schinke, T., 15.12.2015, In : HUM MOL GENET. 24, 24, p. 7075-7086

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  49. Erratum for "Treatment of multifocal breast cancer by systemic delivery of dual-targeted adeno-associated viral vectors"

    Trepel, M., Körbelin, J., Spies, E., Heckmann, M. B., Hunger, A., Fehse, B., Katus, H. A., Kleinschmidt, J. A., Müller, O. J. & Michelfelder, S., 10.2015, In : GENE THER. 22, 10, p. 840-847

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  50. Treatment of multifocal breast cancer by systemic delivery of dual-targeted adeno-associated viral vectors

    Trepel, M., Körbelin, J., Spies, E., Heckmann, M. B., Hunger, A., Fehse, B., Katus, H. A., Kleinschmidt, J. A., Müller, O. J. & Michelfelder, S., 10.2015, In : GENE THER. 22, 10, p. 840-7 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  51. Gezielter CCR5-Knockout in primären T-Lymphozyten zur Verhinderung der HIV-Infektion

    Mock, U. & Fehse, B., 09.2015, Connexi. The Paideia Group, Vol. 6-2015. p. 14-16 3 p.

    Research output: SCORING: Book or contribution to book/anthologyConference contribution - Article for conferenceResearchpeer-review

  52. Übersicht - Gentherapeutische Konzepte in der Onkologie

    Abramowski, P. & Fehse, B., 09.2015, In : Tumor Diagnostik & Therapie. 36, 06, p. 333-336

    Research output: SCORING: Contribution to journalSCORING: Journal articles Research

  53. Combined Application of RGB Marking and Mass Spectrometric Imaging Facilitates Detection of Tumor Heterogeneity

    Abramowski, P., Kraus, O., Rohn, S., Riecken, K., Fehse, B. & Schlüter, H., 03.07.2015, In : Cancer Genomics & Proteomics. 12, 4, p. 179-187 9 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  54. Donor choice in haploidentical stem cell transplantation: fetal microchimerism is associated with better outcome in pediatric leukemia patients

    Kruchen, A., Stahl, T., Gieseke, F., Binder, T. M. C., Özcan, Z., Meisel, R., Kreyenberg, H., Bader, P., Gruhn, B., Greil, J., Pfeiffer, M., Döring, M., Handgretinger, R., Fehse, B. & Müller, I., 22.06.2015, In : BONE MARROW TRANSPL. 50, 10, p. 1367-1370

    Research output: SCORING: Contribution to journalOther (editorial matter etc.)Research

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