Prof.Dr.rer.nat ID: 15692247

Immo Prinz

graph of relations

Publications

  1. 2021
  2. γδT Cells Are Essential for Orthodontic Tooth Movement

    Wald, S., Leibowitz, A., Aizenbud, Y., Saba, Y., Zubeidat, K., Barel, O., Koren, N., Heyman, O., Wilharm, A., Sandrock, I., Fleissig, O., Tal, Y., Prinz, I., Aizenbud, D., Chaushu, S. & Hovav, A. H., 07.2021, In : J DENT RES. 100, 7, p. 731-738 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  3. Enhanced differentiation of functional human T cells in NSGW41 mice with tissue-specific expression of human interleukin-7

    Coppin, E., Sundarasetty, B. S., Rahmig, S., Blume, J., Verheyden, N. A., Bahlmann, F., Ravens, S., Schubert, U., Schmid, J., Ludwig, S., Geissler, K., Guntinas-Lichius, O., von Kaisenberg, C., Groten, T., Platz, A., Naumann, R., Ludwig, B., Prinz, I., Waskow, C. & Krueger, A., 05.2021, In : LEUKEMIA.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  4. Influenza A virus-induced thymus atrophy differentially affects dynamics of conventional and regulatory T cell development in mice

    Elfaki, Y., Robert, P. A., Binz, C., Falk, C. S., Bruder, D., Prinz, I., Floess, S., Meyer-Hermann, M. & Huehn, J., 05.2021, In : EUR J IMMUNOL. 51, 5, p. 1166-1181 16 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  5. A fetal wave of human type 3 effector γδ cells with restricted TCR diversity persists into adulthood

    Tan, L., Fichtner, A. S., Bruni, E., Odak, I., Sandrock, I., Bubke, A., Borchers, A., Schultze-Florey, C., Koenecke, C., Förster, R., Jarek, M., von Kaisenberg, C., Schulz, A., Chu, X., Zhang, B., Li, Y., Panzer, U., Krebs, C. F., Ravens, S. & Prinz, I., 23.04.2021, In : Sci Immunol. 6, 58

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  6. Maturation of the neonatal oral mucosa involves unique epithelium-microbiota interactions

    Koren, N., Zubeidat, K., Saba, Y., Horev, Y., Barel, O., Wilharm, A., Heyman, O., Wald, S., Eli-Berchoer, L., Shapiro, H., Nadler, C., Elinav, E., Wilensky, A., Prinz, I., Bercovier, H. & Hovav, A-H., 10.02.2021, In : CELL HOST MICROBE. 29, 2, p. 197-209.e5

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  7. IL-17 controls central nervous system autoimmunity through the intestinal microbiome

    Regen, T., Isaac, S., Amorim, A., Núñez, N. G., Hauptmann, J., Shanmugavadivu, A., Klein, M., Sankowski, R., Mufazalov, I. A., Yogev, N., Huppert, J., Wanke, F., Witting, M., Grill, A., Gálvez, E. J. C., Nikolaev, A., Blanfeld, M., Prinz, I., Schmitt-Kopplin, P., Strowig, T., Reinhardt, C., Prinz, M., Bopp, T., Becher, B., Ubeda, C. & Waisman, A., 05.02.2021, In : Sci Immunol. 6, 56

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  8. Peritoneal dialysate-range hypertonic glucose promotes T-cell IL-17 production that induces mesothelial inflammation

    Helmke, A., Hüsing, A. M., Gaedcke, S., Brauns, N., Balzer, M. S., Reinhardt, M., Hiss, M., Shushakova, N., de Luca, D., Prinz, I., Haller, H. & von Vietinghoff, S., 02.2021, In : EUR J IMMUNOL. 51, 2, p. 354-367 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  9. Correction: Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance

    Wilharm, A., Brigas, H. C., Sandrock, I., Ribeiro, M., Amado, T., Reinhardt, A., Demera, A., Hoenicke, L., Strowig, T., Carvalho, T., Prinz, I. & Ribot, J. C., 01.2021, In : Mucosal Immunol. 14, 1, p. 278

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  10. Microbiota-dependent expansion of testicular IL-17-producing Vγ6+ γδ T cells upon puberty promotes local tissue immune surveillance

    Wilharm, A., Brigas, H. C., Sandrock, I., Ribeiro, M., Amado, T., Reinhardt, A., Demera, A., Hoenicke, L., Strowig, T., Carvalho, T., Prinz, I. & Ribot, J. C., 01.2021, In : Mucosal Immunol. 14, 1, p. 242-252 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  11. 2020
  12. Synthetic retinoid AM80 inhibits IL-17 production of gamma delta T cells and ameliorates biliary atresia in mice

    Möhn, N., Bruni, E., Schröder, A., Frömmel, S., Gueler, F., Vieten, G., Prinz, I., Kuebler, J. F., Petersen, C. & Klemann, C., 12.2020, In : LIVER INT. 40, 12, p. 3031-3041 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  13. From basic research to clinical application of γδ T cells

    Déchanet-Merville, J. & Prinz, I., 11.2020, In : Immunological reviews. 298, 1, p. 5-9 5 p.

    Research output: SCORING: Contribution to journalSCORING: Review articlesResearch

  14. Ligand recognition by the γδ TCR and discrimination between homeostasis and stress conditions

    Deseke, M. & Prinz, I., 09.2020, In : CELL MOL IMMUNOL. 17, 9, p. 914-924 11 p.

    Research output: SCORING: Contribution to journalSCORING: Review articlesResearch

  15. PD-L1 Checkpoint Inhibition Narrows the Antigen-Specific T Cell Receptor Repertoire in Chronic Lymphocytic Choriomeningitis Virus Infection

    Klein, S., Ghersi, D., Manns, M. P., Prinz, I., Cornberg, M. & Kraft, A. R. M., 31.08.2020, In : J VIROL. 94, 18

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  16. Microbial exposure drives polyclonal expansion of innate γδ T cells immediately after birth

    Ravens, S., Fichtner, A. S., Willers, M., Torkornoo, D., Pirr, S., Schöning, J., Deseke, M., Sandrock, I., Bubke, A., Wilharm, A., Dodoo, D., Egyir, B., Flanagan, K. L., Steinbrück, L., Dickinson, P., Ghazal, P., Adu, B., Viemann, D. & Prinz, I., 04.08.2020, In : P NATL ACAD SCI USA. 117, 31, p. 18649-18660 12 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  17. IL-17 regulates DC migration to the peribronchial LNs and allergen presentation in experimental allergic asthma

    Jirmo, A. C., Busse, M., Happle, C., Skuljec, J., Dalüge, K., Habener, A., Grychtol, R., DeLuca, D. S., Breiholz, O. D., Prinz, I. & Hansen, G., 07.2020, In : EUR J IMMUNOL. 50, 7, p. 1019-1033 15 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  18. Reappearance of effector T cells is associated with recovery from COVID-19

    Odak, I., Barros-Martins, J., Bošnjak, B., Stahl, K., David, S., Wiesner, O., Busch, M., Hoeper, M. M., Pink, I., Welte, T., Cornberg, M., Stoll, M., Goudeva, L., Blasczyk, R., Ganser, A., Prinz, I., Förster, R., Koenecke, C. & Schultze-Florey, C. R., 07.2020, In : EBioMedicine. 57, p. 102885

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  19. TCR repertoire analysis reveals phosphoantigen-induced polyclonal proliferation of Vγ9Vδ2 T cells in neonates and adults

    Fichtner, A. S., Bubke, A., Rampoldi, F., Tan, L., Wilharm, A., Steinbrück, L., Schultze-Florey, C., von Kaisenberg, C., Prinz, I., Herrmann, T. & Ravens, S., 06.2020, In : J LEUKOCYTE BIOL. 107, 6, p. 1023-1032 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  20. Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice

    Moyé, S., Bormann, T., Maus, R., Sparwasser, T., Sandrock, I., Prinz, I., Warnecke, G., Welte, T., Gauldie, J., Kolb, M. & Maus, U. A., 01.05.2020, In : J IMMUNOL. 204, 9, p. 2429-2438 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  21. Development and Function of γδT Cells in the Oral Mucosa

    Hovav, A. H., Wilharm, A., Barel, O. & Prinz, I., 05.2020, In : J DENT RES. 99, 5, p. 498-505 8 p.

    Research output: SCORING: Contribution to journalSCORING: Review articlesResearch

  22. γδ T-cell Receptors Derived from Breast Cancer-Infiltrating T Lymphocytes Mediate Antitumor Reactivity

    Janssen, A., Villacorta Hidalgo, J., Beringer, D. X., van Dooremalen, S., Fernando, F., van Diest, E., Terrizi, A. R., Bronsert, P., Kock, S., Schmitt-Gräff, A., Werner, M., Heise, K., Follo, M., Straetemans, T., Sebestyen, Z., Chudakov, D. M., Kasatskaya, S. A., Frenkel, F. E., Ravens, S., Spierings, E., Prinz, I., Küppers, R., Malkovsky, M., Fisch, P. & Kuball, J., 04.2020, In : Cancer immunology research. 8, 4, p. 530-543 14 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  23. Human γδ TCR Repertoires in Health and Disease

    Fichtner, A. S., Ravens, S. & Prinz, I., 26.03.2020, In : Cells. 9, 4

    Research output: SCORING: Contribution to journalSCORING: Review articlesResearch

  24. Revisiting the Interaction of γδ T-Cells and B-Cells

    Rampoldi, F., Ullrich, L. & Prinz, I., 18.03.2020, In : Cells. 9, 3

    Research output: SCORING: Contribution to journalSCORING: Review articlesResearch

  25. Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies

    Sebestyen, Z., Prinz, I., Déchanet-Merville, J., Silva-Santos, B. & Kuball, J., 03.2020, In : NAT REV DRUG DISCOV. 19, 3, p. 169-184 16 p.

    Research output: SCORING: Contribution to journalSCORING: Review articlesResearch

  26. Interleukin-17 cytokines: Effectors and targets in psoriasis-A breakthrough in understanding and treatment

    Prinz, I., Sandrock, I. & Mrowietz, U., 06.01.2020, In : J EXP MED. 217, 1

    Research output: SCORING: Contribution to journalSCORING: Review articlesResearch

  27. Donor-derived IL-17A and IL-17F deficiency triggers Th1 allo-responses and increases gut leakage during acute GVHD

    Odak, I., Depkat-Jakob, A., Beck, M., Jarek, M., Yu, Y., Seidler, U., David, S., Ganser, A., Förster, R., Prinz, I. & Koenecke, C., 2020, In : PLOS ONE. 15, 4, p. e0231222

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  28. 2019
  29. NKp46-expressing human gut-resident intraepithelial Vδ1 T cell subpopulation exhibits high antitumor activity against colorectal cancer

    Mikulak, J., Oriolo, F., Bruni, E., Roberto, A., Colombo, F. S., Villa, A., Bosticardo, M., Bortolomai, I., Lo Presti, E., Meraviglia, S., Dieli, F., Vetrano, S., Danese, S., Della Bella, S., Carvello, M. M., Sacchi, M., Cugini, G., Colombo, G., Klinger, M., Spaggiari, P., Roncalli, M., Prinz, I., Ravens, S., di Lorenzo, B., Marcenaro, E., Silva-Santos, B., Spinelli, A. & Mavilio, D., 19.12.2019, In : JCI Insight. 4, 24

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  30. Focusing of the regulatory T-cell repertoire after allogeneic stem cell transplantation indicates protection from graft-versus-host disease

    Odak, I., Raha, S., Schultze-Florey, C., Tavil, S., Ravens, S., Ganser, A., Förster, R., Prinz, I. & Koenecke, C., 12.2019, In : HAEMATOLOGICA. 104, 12, p. e577-e580

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  31. Dangerous γδ T cells in aged mice

    Prinz, I. & Sandrock, I., 08.2019, In : EMBO REP. 20, 8, p. e48678

    Research output: SCORING: Contribution to journalSCORING: Review articlesResearch

  32. Styk1 is specifically expressed in NK1.1+ lymphocytes including NK, γδ T, and iNKT cells in mice, but is dispensable for their ontogeny and function

    Wilharm, A., Sandrock, I., Marotel, M., Demera, A., Naumann, R., Walzer, T. & Prinz, I., 05.2019, In : EUR J IMMUNOL. 49, 5, p. 686-693 8 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  33. Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells

    Di Lorenzo, B., Simões, A. E., Caiado, F., Tieppo, P., Correia, D. V., Carvalho, T., da Silva, M. G., Déchanet-Merville, J., Schumacher, T. N., Prinz, I., Norell, H., Ravens, S., Vermijlen, D. & Silva-Santos, B., 04.2019, In : Cancer immunology research. 7, 4, p. 552-558 7 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  34. Robust Identification of Suitable T-Cell Subsets for Personalized CMV-Specific T-Cell Immunotherapy Using CD45RA and CD62L Microbeads

    Mangare, C., Tischer-Zimmermann, S., Riese, S. B., Dragon, A. C., Prinz, I., Blasczyk, R., Maecker-Kolhoff, B. & Eiz-Vesper, B., 20.03.2019, In : INT J MOL SCI. 20, 6

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  35. Germ Line Deletion Reveals a Nonessential Role of Atypical Mitogen-Activated Protein Kinase 6/Extracellular Signal-Regulated Kinase 3

    Ronkina, N., Schuster-Gossler, K., Hansmann, F., Kunze-Schumacher, H., Sandrock, I., Yakovleva, T., Lafera, J., Baumgärtner, W., Krueger, A., Prinz, I., Gossler, A., Kotlyarov, A. & Gaestel, M., 15.03.2019, In : MOL CELL BIOL. 39, 6

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  36. The Skin Commensal Yeast Malassezia Triggers a Type 17 Response that Coordinates Anti-fungal Immunity and Exacerbates Skin Inflammation

    Sparber, F., De Gregorio, C., Steckholzer, S., Ferreira, F. M., Dolowschiak, T., Ruchti, F., Kirchner, F. R., Mertens, S., Prinz, I., Joller, N., Buch, T., Glatz, M., Sallusto, F. & LeibundGut-Landmann, S., 13.03.2019, In : CELL HOST MICROBE. 25, 3, p. 389-403.e6

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  37. miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

    Łyszkiewicz, M., Winter, S. J., Witzlau, K., Föhse, L., Brownlie, R., Puchałka, J., Verheyden, N. A., Kunze-Schumacher, H., Imelmann, E., Blume, J., Raha, S., Sekiya, T., Yoshimura, A., Frueh, J. T., Ullrich, E., Huehn, J., Weiss, S., Gutierrez, M. G., Prinz, I., Zamoyska, R., Ziętara, N. & Krueger, A., 03.2019, In : PLOS BIOL. 17, 3, p. e2006716

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  38. Mutual interplay between IL-17-producing γδT cells and microbiota orchestrates oral mucosal homeostasis

    Wilharm, A., Tabib, Y., Nassar, M., Reinhardt, A., Mizraji, G., Sandrock, I., Heyman, O., Barros-Martins, J., Aizenbud, Y., Khalaileh, A., Eli-Berchoer, L., Elinav, E., Wilensky, A., Förster, R., Bercovier, H., Prinz, I. & Hovav, A-H., 12.02.2019, In : P NATL ACAD SCI USA. 116, 7, p. 2652-2661 10 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  39. Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy

    Soon, C. F., Zhang, S., Suneetha, P. V., Antunes, D. A., Manns, M. P., Raha, S., Schultze-Florey, C., Prinz, I., Wedemeyer, H., Sällberg Chen, M. & Cornberg, M., 2019, In : Frontiers in Immunology. 10, p. 2076

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  40. 2018
  41. Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells

    Sandrock, I., Reinhardt, A., Ravens, S., Binz, C., Wilharm, A., Martins, J., Oberdörfer, L., Tan, L., Lienenklaus, S., Zhang, B., Naumann, R., Zhuang, Y., Krueger, A., Förster, R. & Prinz, I., 03.12.2018, In : The Journal of experimental medicine. 215, 12, p. 3006-3018 13 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  42. Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells

    Hammer, Q., Rückert, T., Borst, E. M., Dunst, J., Haubner, A., Durek, P., Heinrich, F., Gasparoni, G., Babic, M., Tomic, A., Pietra, G., Nienen, M., Blau, I. W., Hofmann, J., Na, I-K., Prinz, I., Koenecke, C., Hemmati, P., Babel, N., Arnold, R., Walter, J., Thurley, K., Mashreghi, M-F., Messerle, M. & Romagnani, C., 05.2018, In : Nature Immunology. 19, 5, p. 453-463 11 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  43. The neonatal window of opportunity-early priming for life

    Renz, H., Adkins, B. D., Bartfeld, S., Blumberg, R. S., Farber, D. L., Garssen, J., Ghazal, P., Hackam, D. J., Marsland, B. J., McCoy, K. D., Penders, J., Prinz, I., Verhasselt, V., von Mutius, E., Weiser, J. N., Wesemann, D. R. & Hornef, M. W., 04.2018, In : J ALLERGY CLIN IMMUN. 141, 4, p. 1212-1214 3 p.

    Research output: SCORING: Contribution to journalSCORING: Journal articles Researchpeer-review

  44. Whodunit? The Contribution of Interleukin (IL)-17/IL-22-Producing γδ T Cells, αβ T Cells, and Innate Lymphoid Cells to the Pathogenesis of Spondyloarthritis

    Reinhardt, A. & Prinz, I., 04.2018, In : Frontiers in Immunology. 9, p. 885

    Research output: SCORING: Contribution to journalSCORING: Review articlesResearch

  45. Innately versatile: γδ17 T cells in inflammatory and autoimmune diseases

    Papotto, P. H., Reinhardt, A., Prinz, I. & Silva-Santos, B., 02.2018, In : J AUTOIMMUN. 87, p. 26-37 12 p.

    Research output: SCORING: Contribution to journalSCORING: Review articlesResearch