Research ExplorerScientific StaffMartin Horstmann Publications

Prof. Dr. ID: 52993

Martin Horstmann

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Publications

  1. 2022

  2. Amsacrine combined with etoposide and methylprednisolone is a feasible and safe component in first-line intensified treatment of pediatric patients with high-risk acute lymphoblastic leukemia in CoALL08-09 trial

    Mezger, K., Ebert, S., Muhle, H. E., Stadt, U. Z., Borkhardt, A., Dilloo, D., Faber, J., Feuchtinger, T., Imschweiler, T., Jorch, N., Pekrun, A., Schmid, I., Schramm, F., Zimmermann, M., Horstmann, M. A. & Escherich, G., 12.2022, In: PEDIATR BLOOD CANCER. 69, 12, e29997.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  3. Clofarabine increases the eradication of minimal residual disease of primary B-precursor acute lymphoblastic leukemia compared to high-dose cytarabine without improvement of outcome. Results from the randomized clinical trial 08-09 of the Cooperative Acute Lymphoblastic Leukemia Study Group

    Escherich, G., Zur Stadt, U., Borkhardt, A., Dilloo, D., Faber, J., Feuchtinger, T., Imschweiler, T., Jorch, N., Pekrun, A., Schmid, I., Schramm, F., Spohn, M., Zimmermann, M. & Horstmann, M. A., 01.05.2022, In: HAEMATOLOGICA. 107, 5, p. 1026-1033 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  4. Akute lymphoblastische Leukämie

    Escherich, G., Möricke, A., Horstmann, M. & Schrappe, M., 15.02.2022, Kompendium Internistische Onkologie: Standards in Diagnostik und Therapie. Schmoll, H-J. (ed.). 5 ed. Berlin, Heidelberg: Springer, 11 p.

    Research output: SCORING: Book or contribution to book/anthology › Chapter › Research › peer-review

  5. 2021

  6. Genome-wide interference of ZNF423 with B-lineage transcriptional circuitries in acute lymphoblastic leukemia

    Iglesias, P., Puller, A-C., Seoane, M., Spohn, M., Raasch, S., Klokow, M., Müller, J., Burkhardt, L., Indenbirken, D. & Horstmann, M. A., 09.03.2021, In: BLOOD ADV. 5, 5, p. 1209-1223 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  7. 2020

  8. Leukemia-induced dysfunctional TIM-3+CD4+ bone marrow T cells increase risk of relapse in pediatric B-precursor ALL patients

    Blaeschke, F., Willier, S., Stenger, D., Lepenies, M., Horstmann, M. A., Escherich, G., Zimmermann, M., Rojas Ringeling, F., Canzar, S., Kaeuferle, T., Rohlfs, M., Binder, V., Klein, C. & Feuchtinger, T., 10.2020, In: LEUKEMIA. 34, 10, p. 2607-2620 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  9. A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia

    Enshaei, A., O'Connor, D., Bartram, J., Hancock, J., Harrison, C. J., Hough, R., Samarasinghe, S., den Boer, M. L., Boer, J. M., de Groot-Kruseman, H. A., Marquart, H. V., Noren-Nystrom, U., Schmiegelow, K., Schwab, C., Horstmann, M. A., Escherich, G., Heyman, M., Pieters, R., Vora, A., Moppett, J. & Moorman, A. V., 23.04.2020, In: BLOOD. 135, 17, p. 1438-1446 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  10. 2019

  11. Characterization of novel, recurrent genomic rearrangements as sensitive MRD targets in childhood B-cell precursor ALL

    Zur Stadt, U., Alawi, M., Adao, M., Indenbirken, D., Escherich, G. & Horstmann, M. A., 29.11.2019, In: BLOOD CANCER J. 9, 12, p. 96

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  12. Results of CoALL 07-03 study childhood ALL based on combined risk assessment by in vivo and in vitro pharmacosensitivity

    Schramm, F., Zur Stadt, U., Zimmermann, M., Jorch, N., Pekrun, A., Borkhardt, A., Imschweiler, T., Christiansen, H., Faber, J., Schmid, I., Feuchtinger, T., Beron, G., den Boer, M. L., Pieters, R., Horstmann, M. A., Janka-Schaub, G. E. & Escherich, G., 26.11.2019, In: Blood Adv. 3, 22, p. 3688-3699 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  13. High sensitivity and clonal stability of the genomic fusion as single marker for response monitoring in ETV6-RUNX1-positive acute lymphoblastic leukemia

    Hoffmann, J., Krumbholz, M., Gutiérrez, H. P., Fillies, M., Szymansky, A., Bleckmann, K., Zur Stadt, U., Köhler, R., Kuiper, R. P., Horstmann, M., von Stackelberg, A., Eckert, C. & Metzler, M., 08.2019, In: PEDIATR BLOOD CANCER. 66, 8, p. e27780

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  14. PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia

    Bastian, L., Schroeder, M. P., Eckert, C., Schlee, C., Tanchez, J. O., Kämpf, S., Wagner, D. L., Schulze, V., Isaakidis, K., Lázaro-Navarro, J., Hänzelmann, S., James, A. R., Ekici, A., Burmeister, T., Schwartz, S., Schrappe, M., Horstmann, M., Vosberg, S., Krebs, S., Blum, H., Hecht, J., Greif, P. A., Rieger, M. A., Brüggemann, M., Gökbuget, N., Neumann, M. & Baldus, C. D., 08.2019, In: LEUKEMIA. 33, 8, p. 1895-1909 15 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  15. IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia

    Lopes, B. A., Meyer, C., Barbosa, T. C., Poubel, C. P., Mansur, M. B., Duployez, N., Bashton, M., Harrison, C. J., Zur Stadt, U., Horstmann, M., Pombo-de-Oliveira, M. S., Palmi, C., Cazzaniga, G., Venn, N. C., Sutton, R., Alonso, C. N., Tsaur, G., Gupta, S. K., Bakhshi, S., Marschalek, R. & Emerenciano, M., 05.2019, In: TRANSL ONCOL. 12, 5, p. 726-732 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  16. Lineage-specific control of TFIIH by MITF determines transcriptional homeostasis and DNA repair

    Seoane, M., Buhs, S., Iglesias, P., Strauss, J., Puller, A-C., Müller, J., Gerull, H., Feldhaus, S., Alawi, M., Brandner, J. M., Eggert, D., Du, J., Thomale, J., Wild, P. J., Zimmermann, M., Sternsdorf, T., Schumacher, U., Nollau, P., Fisher, D. E. & Horstmann, M. A., 05.2019, In: ONCOGENE. 38, 19, p. 3616-3635 20 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  17. Copy number alterations in B-cell development genes, drug resistance, and clinical outcome in pediatric B-cell precursor acute lymphoblastic leukemia

    Steeghs, E. M. P., Boer, J. M., Hoogkamer, A. Q., Boeree, A., de Haas, V., de Groot-Kruseman, H. A., Horstmann, M. A., Escherich, G., Pieters, R. & den Boer, M. L., 15.03.2019, In: SCI REP-UK. 9, 1, p. 4634

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  18. Daunorubicin during delayed intensification decreases the incidence of infectious complications - a randomized comparison in trial CoALL 08-09

    Schramm, F., Zimmermann, M., Jorch, N., Pekrun, A., Borkhardt, A., Imschweiler, T., Christiansen, H., Faber, J., Feuchtinger, T., Schmid, I., Beron, G., Horstmann, M. A. & Escherich, G., 01.2019, In: LEUKEMIA LYMPHOMA. 60, 1, p. 60-68 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  19. 2018

  20. Combined inhibition of receptor tyrosine and p21-activated kinases as a therapeutic strategy in childhood ALL

    Siekmann, I-K., Dierck, K., Prall, S., Klokow, M., Strauss, J., Buhs, S., Wrzeszcz, A., Bockmayr, M., Beck, F., Trochimiuk, M., Gottschling, K., Martens, V., Khosh-Naucke, M., Gerull, H., Müller, J., Behrmann, L., Blohm, M., Zahedi, R. P., Jeremias, I., Sickmann, A., Nollau, P. & Horstmann, M. A., 09.10.2018, In: Blood Adv. 2, 19, p. 2554-2567 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  21. Pediatric acute lymphoblastic leukemia-Conquering the CNS across the choroid plexus

    März, M., Meyer, S., Erb, U., Georgikou, C., Horstmann, M. A., Hetjens, S., Weiß, C., Fallier-Becker, P., Vandenhaute, E., Ishikawa, H., Schroten, H., Dürken, M. & Karremann, M., 08.2018, In: LEUKEMIA RES. 71, p. 47-54 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  22. RAS pathway mutations as a predictive biomarker for treatment adaptation in pediatric B-cell precursor acute lymphoblastic leukemia

    Jerchel, I. S., Hoogkamer, A. Q., Ariës, I. M., Steeghs, E. M. P., Boer, J. M., Besselink, N. J. M., Boeree, A., van de Ven, C., de Groot-Kruseman, H. A., de Haas, V., Horstmann, M. A., Escherich, G., Zwaan, C. M., Cuppen, E., Koudijs, M. J., Pieters, R. & den Boer, M. L., 04.2018, In: LEUKEMIA. 32, 4, p. 931-940 10 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  23. 2017

  24. The role of constitutive activation of FMS-related tyrosine kinase-3 andmutational status in infants with-rearranged acute lymphoblastic leukemia

    Fedders, H., Alsadeq, A., Schmäh, J., Vogiatzi, F., Zimmermann, M., Möricke, A., Lenk, L., Stadt, U. Z., Horstmann, M. A., Pieters, R., Schrappe, M., Stanulla, M., Cario, G. & Schewe, D. M., 11.2017, In: HAEMATOLOGICA. 102, 11, p. e438-e442

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  25. JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia

    Steeghs, E. M. P., Jerchel, I. S., de Goffau-Nobel, W., Hoogkamer, A. Q., Boer, J. M., Boeree, A., van de Ven, C., Koudijs, M. J., Besselink, N. J. M., de Groot-Kruseman, H. A., Zwaan, C. M., Horstmann, M. A., Pieters, R. & den Boer, M. L., 27.10.2017, In: ONCOTARGET. 8, 52, p. 89923-89938 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  26. Genomic and transcriptional landscape of P2RY8-CRLF2-positive childhood acute lymphoblastic leukemia

    Vesely, C., Frech, C., Eckert, C., Cario, G., Mecklenbräuker, A., Zur Stadt, U., Nebral, K., Kraler, F., Fischer, S., Attarbaschi, A., Schuster, M., Bock, C., Cavé, H., von Stackelberg, A., Schrappe, M., Horstmann, M. A., Mann, G., Haas, O. A. & Panzer-Grümayer, R., 07.2017, In: LEUKEMIA. 31, 7, p. 1491-1501

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  27. Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology

    Ripperger, T., Bielack, S. S., Borkhardt, A., Brecht, I. B., Burkhardt, B., Calaminus, G., Debatin, K-M., Deubzer, H., Dirksen, U., Eckert, C., Eggert, A., Erlacher, M., Fleischhack, G., Frühwald, M. C., Gnekow, A., Goehring, G., Graf, N., Hanenberg, H., Hauer, J., Hero, B., Hettmer, S., von Hoff, K., Horstmann, M., Hoyer, J., Illig, T., Kaatsch, P., Kappler, R., Kerl, K., Klingebiel, T., Kontny, U., Kordes, U., Körholz, D., Koscielniak, E., Kramm, C. M., Kuhlen, M., Kulozik, A. E., Lamottke, B., Leuschner, I., Lohmann, D. R., Meinhardt, A., Metzler, M., Meyer, L. H., Moser, O., Nathrath, M., Niemeyer, C. M., Nustede, R., Pajtler, K. W., Paret, C., Rasche, M., Reinhardt, D., Rieß, O., Russo, A., Rutkowski, S., Schlegelberger, B., Schneider, D., Schneppenheim, R., Schrappe, M., Schroeder, C., von Schweinitz, D., Simon, T., Sparber-Sauer, M., Spix, C., Stanulla, M., Steinemann, D., Strahm, B., Temming, P., Thomay, K., von Bueren, A. O., Vorwerk, P., Witt, O., Wlodarski, M., Wössmann, W., Zenker, M., Zimmermann, S., Pfister, S. M. & Kratz, C. P., 04.2017, In: AM J MED GENET A. 173, 4, p. 1017-1037 21 p.

    Research output: SCORING: Contribution to journal › SCORING: Review articles › Research

  28. Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome

    Witkowski, M. T., Hu, Y., Roberts, K. G., Boer, J. M., McKenzie, M. D., Liu, G. J., Le Grice, O. D., Tremblay, C. S., Ghisi, M., Willson, T. A., Horstmann, M. A., Aifantis, I., Cimmino, L., Frietze, S., den Boer, M. L., Mullighan, C. G., Smyth, G. K. & Dickins, R. A., 06.03.2017, In: J EXP MED. 214, 3, p. 773-791 19 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  29. Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients

    Scheijen, B., Boer, J. M., Marke, R., Tijchon, E., van Ingen Schenau, D., Waanders, E., van Emst, L., van der Meer, L. T., Pieters, R., Escherich, G., Horstmann, M., Sonneveld, E., Venn, N., Sutton, R., Dalla-Pozza, L., Kuiper, R. P., Hoogerbrugge, P. M., den Boer, M. L. & van Leeuwen, F. N., 03.2017, In: HAEMATOLOGICA. 102, 3, p. 541-551

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  30. 2016

  31. IL-7 Receptor Mutations and Steroid Resistance in Pediatric T cell Acute Lymphoblastic Leukemia: A Genome Sequencing Study

    Li, Y., Buijs-Gladdines, J. G. C. A. M., Canté-Barrett, K., Stubbs, A. P., Vroegindeweij, E. M., Smits, W. K., van Marion, R., Dinjens, W. N. M., Horstmann, M., Kuiper, R. P., Buijsman, R. C., Zaman, G. J. R., van der Spek, P. J., Pieters, R. & Meijerink, J. P. P., 12.2016, In: PLOS MED. 13, 12, p. e1002200

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  32. COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia

    Lopes, B. A., Meyer, C., Barbosa, T. C., Stadt, U. Z., Horstmann, M., Venn, N. C., Heatley, S., White, D. L., Sutton, R., Pombo-de-Oliveira, M. S., Marschalek, R. & Emerenciano, M., 13.07.2016, In: ONCOTARGET. 7, 33, p. 53064-53073

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  33. Rapid Capture Next-Generation Sequencing in Clinical Diagnostics of Kinase Pathway Aberrations in B-Cell Precursor ALL

    Stadt, U. Z., Escherich, G., Indenbirken, D., Alawi, M., Adao, M. & Horstmann, M. A., 23.03.2016, In: PEDIATR BLOOD CANCER. 63, 7, p. 1283-6

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  34. Prognostic value of rare IKZF1 deletion in childhood B-cell precursor acute lymphoblastic leukemia: an international collaborative study

    Boer, J. M., van der Veer, A., Rizopoulos, D., Fiocco, M., Sonneveld, E., de Groot-Kruseman, H. A., Kuiper, R. P., Hoogerbrugge, P., Horstmann, M., Zaliova, M., Palmi, C., Trka, J., Fronkova, E., Emerenciano, M., do Socorro Pombo-de-Oliveira, M., Mlynarski, W., Szczepanski, T., Nebral, K., Attarbaschi, A., Venn, N., Sutton, R., Schwab, C. J., Enshaei, A., Vora, A., Stanulla, M., Schrappe, M., Cazzaniga, G., Conter, V., Zimmermann, M., Moorman, A. V., Pieters, R. & den Boer, M. L., 01.2016, In: LEUKEMIA. 30, 1, p. 32-8 7 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  35. 2015

  36. BCR-ABL1-like cases in pediatric acute lymphoblastic leukemia: a comparison between DCOG/Erasmus MC and COG/St. Jude signatures

    Boer, J. M., Marchante, J. R. M., Evans, W. E., Horstmann, M. A., Escherich, G., Pieters, R. & Den Boer, M. L., 09.2015, In: HAEMATOLOGICA. 100, 9, p. e354-7

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  37. KRAS and CREBBP mutations: a relapse-linked malicious liaison in childhood high hyperdiploid acute lymphoblastic leukemia

    Malinowska-Ozdowy, K., Frech, C., Schönegger, A., Eckert, C., Cazzaniga, G., Stanulla, M., Zur Stadt, U., Mecklenbräuker, A., Schuster, M., Kneidinger, D., von Stackelberg, A., Locatelli, F., Schrappe, M., Horstmann, M. A., Attarbaschi, A., Bock, C., Mann, G., Haas, O. A. & Panzer-Grümayer, R., 28.04.2015, In: LEUKEMIA. 29, 8, p. 1656-1667

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  38. A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma progression

    Dadras, S. S., Lin, R. J., Razavi, G., Kawakami, A., Du, J., Feige, E., Milner, D. A., Loda, M. F., Granter, S. R., Detmar, M., Widlund, H. R., Horstmann, M. A. & Fisher, D. E., 01.2015, In: AM J PATHOL. 185, 1, p. 252-65 14 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  39. 2014

  40. The PML domain of PML-RARα blocks senescence to promote leukemia

    Korf, K., Wodrich, H., Haschke, A., Ocampo, C., Harder, L., Gieseke, F., Pollmann, A., Dierck, K., Prall, S., Staege, H., Ma, H., Horstmann, M. A., Evans, R. M. & Sternsdorf, T., 19.08.2014, In: P NATL ACAD SCI USA. 111, 33, p. 12133-8 6 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  41. PTEN microdeletions in T-cell acute lymphoblastic leukemia are caused by illegitimate RAG-mediated recombination events

    Mendes, R. D., Sarmento, L. M., Canté-Barrett, K., Zuurbier, L., Buijs-Gladdines, J. G. C. A. M., Póvoa, V., Smits, W. K., Abecasis, M., Yunes, J. A., Sonneveld, E., Horstmann, M. A., Pieters, R., Barata, J. T. & Meijerink, J. P. P., 24.07.2014, In: BLOOD. 124, 4, p. 567-78 12 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  42. Identification of novel NOTCH1 mutations: increasing our knowledge of the NOTCH signaling pathway

    Gallo Llorente, L., Luther, H., Schneppenheim, R., Zimmermann, M., Felice, M. & Horstmann, M. A., 01.05.2014, In: PEDIATR BLOOD CANCER. 61, 5, p. 788-96 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  43. EMP1, a novel poor prognostic factor in pediatric leukemia regulates prednisolone resistance, cell proliferation, migration and adhesion

    Ariës, I. M., Jerchel, I. S., van den Dungen, R. E. S. R., van den Berk, L. C. J., Boer, J. M., Horstmann, M. A., Escherich, G., Pieters, R. & den Boer, M. L., 20.02.2014, In: LEUKEMIA. 28, 9, p. 1828-1837

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  44. Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors

    Zuurbier, L., Gutierrez, A., Mullighan, C. G., Canté-Barrett, K., Gevaert, A. O., de Rooi, J., Li, Y., Smits, W. K., Buijs-Gladdines, J. G. C. A. M., Sonneveld, E., Look, A. T., Horstmann, M., Pieters, R. & Meijerink, J. P. P., 01.01.2014, In: HAEMATOLOGICA. 99, 1, p. 94-102 9 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  45. Interference with pre-B-cell receptor signaling offers a therapeutic option for TCF3-rearranged childhood acute lymphoblastic leukemia

    van der Veer, A., van der Velden, V. H. J., Willemse, M. E., Hoogeveen, P. G., Petricoin, E. F., Beverloo, H. B., Escherich, G., Horstmann, M. A., Pieters, R. & den Boer, M. L., 01.01.2014, In: BLOOD CANCER J. 4, p. e181

    Research output: SCORING: Contribution to journal › Other (editorial matter etc.) › Research

  46. 2013

  47. Aberrant ZNF423 impedes B cell differentiation and is linked to adverse outcome of ETV6-RUNX1 negative B precursor acute lymphoblastic leukemia

    Harder, L., Eschenburg, G., Zech, A., Kriebitzsch, N., Otto, B., Streichert, T., Behlich, A-S., Dierck, K., Klingler, B., Hansen, A., Stanulla, M., Zimmermann, M., Kremmer, E., Stocking, C. & Horstmann, M. A., 21.10.2013, In: J EXP MED. 210, 11, p. 2289-304 16 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  48. Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL

    van der Veer, A., Waanders, E., Pieters, R., Willemse, M. E., Van Reijmersdal, S. V., Russell, L. J., Harrison, C. J., Evans, W. E., van der Velden, V. H. J., Hoogerbrugge, P. M., Van Leeuwen, F., Escherich, G., Horstmann, M. A., Mohammadi Khankahdani, L., Rizopoulos, D., De Groot-Kruseman, H. A., Sonneveld, E., Kuiper, R. P. & Den Boer, M. L., 10.10.2013, In: BLOOD. 122, 15, p. 2622-9 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  49. Clofarabine in combination with pegylated asparaginase in the frontline treatment of childhood acute lymphoblastic leukaemia: a feasibility report from the CoALL 08-09 trial

    Escherich, G., Zur Stadt, U., Zimmermann, M., Horstmann, M. A. & COALL study group, 01.10.2013, In: BRIT J HAEMATOL. 163, 2, p. 240-7 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  50. Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells

    Hartsink-Segers, S. A., Exalto, C., Allen, M., Williamson, D., Clifford, S. C., Horstmann, M., Caron, H. N., Pieters, R. & Den Boer, M. L., 01.10.2013, In: HAEMATOLOGICA. 98, 10, p. 1539-46 8 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  51. Refinement of IKZF1 recombination hotspots in pediatric BCP-ALL patients.

    Meyer, C., Zur Stadt, U., Escherich, G., Hofmann, J., Binato, R., Barbosa, T. D. C., Emerenciano, M., Pombo-de-Oliveira, M. S., Horstmann, M. & Marschalek, R., 2013, In: AM J BLOOD RES. 3, 2, p. 165-173 9 p., 2.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  52. 2012

  53. Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.

    Ellinghaus, E., Stanulla, M., Richter, G., Ellinghaus, D., Te Kronnie, G., Cario, G., Cazzaniga, G., Horstmann, M., Panzer Grümayer, R., Cavé, H., Trka, J., Cinek, O., Teigler-Schlegel, A., ElSharawy, A., Häsler, R., Nebel, A., Meissner, B., Bartram, T., Lescai, F., Franceschi, C., Giordan, M., Nürnberg, P., Heinzow, B., Zimmermann, M., Schreiber, S., Schrappe, M. & Franke, A., 2012, In: LEUKEMIA. 26, 5, p. 902-909 5.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  54. In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice.

    Terziyska, N., Catarina, C. A., Groiss, V., Schneider, K., Farkasova, K., Ogris, M., Wagner, E., Ehrhardt, H., Brentjens, R. J., Zur Stadt, U., Horstmann, M., Quintanilla-Martinez, L. & Jeremias, I., 2012, In: PLOS ONE. 7, 12, p. 52798 12.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  55. Leukemia-associated mutations in SHIP1 inhibit its enzymatic activity, interaction with the GM-CSF receptor and Grb2, and its ability to inactivate PI3K/AKT signaling.

    Brauer, H., Strauss, J., Wegner, W., Müller-Tidow, C., Horstmann, M. & Jücker, M., 2012, In: CELL SIGNAL. 24, 11, p. 2095-2101 11.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  56. Quantification of minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL) using amplicon-fusion-site polymerase chain reaction (AFS-PCR).

    Weber, A., Taube, S., Zur Stadt, U., Horstmann, M., Krohn, K., Bradtke, J., Teigler-Schlegel, A., Leiblein, S. & Christiansen, H., 2012, In: EXP HEMATOL ONCOL. 1, 1, p. 33 1.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  57. The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia.

    Zuurbier, L., Petricoin, E. F., Vuerhard, M. J., Calvert, V., Kooi, C., Buijs-Gladdines, J. G. C. A. M., Smits, W. K., Sonneveld, E., Veerman, A. J. P., Kamps, W. A., Horstmann, M., Pieters, R. & Meijerink, J. P. P., 2012, In: HAEMATOLOGICA. 97, 9, p. 1405-1413 9.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  58. 2011

  59. Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.

    Homminga, I., Pieters, R., Langerak, A. W., Rooi, D., Johan, J., Stubbs, A., Verstegen, M., Vuerhard, M., Buijs-Gladdines, J., Kooi, C., Klous, P., van Vlierberghe, P., Ferrando, A. A., Cayuela, J. M., Verhaaf, B., Horstmann, M., Horstmann, M., de Haas, V., Wiekmeijer, A-S., Pike-Overzet, K., Staal, F. J. T., de Laat, W., Soulier, J., Sigaux, F. & Meijerink, J. P. P., 2011, In: CANCER CELL. 19, 4, p. 484-497 4.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  60. Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia.

    Zenatti, P. P., Ribeiro, D., Li, W., Zuurbier, L., Silva, M. C., Paganin, M., Tritapoe, J., Hixon, J. A., Silveira, A. B., Cardoso, B. A., Sarmento, L. M., Correia, N., Toribio, M. L., Kobarg, J., Horstmann, M., Pieters, R., Brandalise, S. R., Ferrando, A. A., Meijerink, J. P., Durum, S. K., Yunes, J. A. & Barata, J. T., 2011, In: NAT GENET. 43, 10, p. 932-939 10.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  61. The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97).

    Escherich, G., Troeger, A. F., Gobel, U., Graubner, U., Pekrun, A., Jorch, N., Kaspers, G., Zimmermann, M., Zur Stadt, U., Kazemir, K., Pieters, R., Horstmann, M., Denboer, M. L. & Janka-Schaub, G., 2011, In: HAEMATOLOGICA. 96, 6, p. 854-862 6.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

  62. 2010

  63. Cooperative study group for childhood acute lymphoblastic leukaemia (COALL): long-term results of trials 82,85,89,92 and 97.

    Escherich, G., Horstmann, M. A., Zimmermann, M., Janka-Schaub, G. E. & COALL study group, 01.02.2010, In: LEUKEMIA. 24, 2, p. 298-308 11 p.

    Research output: SCORING: Contribution to journal › SCORING: Journal articles › Research › peer-review

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