Magnetic particle imaging for assessment of cerebral perfusion and ischemia
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Magnetic particle imaging for assessment of cerebral perfusion and ischemia. / Ludewig, Peter; Graeser, Matthias; Forkert, Nils D; Thieben, Florian; Rández-Garbayo, Javier; Rieckhoff, Johanna; Lessmann, Katrin; Förger, Fynn; Szwargulski, Patryk; Magnus, Tim; Knopp, Tobias.
in: WIRES NANOMED NANOBI, Jahrgang 14, Nr. 1, e1757, 01.2022.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Magnetic particle imaging for assessment of cerebral perfusion and ischemia
AU - Ludewig, Peter
AU - Graeser, Matthias
AU - Forkert, Nils D
AU - Thieben, Florian
AU - Rández-Garbayo, Javier
AU - Rieckhoff, Johanna
AU - Lessmann, Katrin
AU - Förger, Fynn
AU - Szwargulski, Patryk
AU - Magnus, Tim
AU - Knopp, Tobias
N1 - © 2021 The Authors. WIREs Nanomedicine and Nanobiotechnology published by Wiley Periodicals LLC.
PY - 2022/1
Y1 - 2022/1
N2 - Stroke is one of the leading worldwide causes of death and sustained disability. Rapid and accurate assessment of cerebral perfusion is essential to diagnose and successfully treat stroke patients. Magnetic particle imaging (MPI) is a new technology with the potential to overcome some limitations of established imaging modalities. It is an innovative and radiation-free imaging technique with high sensitivity, specificity, and superior temporal resolution. MPI enables imaging and diagnosis of stroke and other neurological pathologies such as hemorrhage, tumors, and inflammatory processes. MPI scanners also offer the potential for targeted therapies of these diseases. Due to lower field requirements, MPI scanners can be designed as resistive magnets and employed as mobile devices for bedside imaging. With these advantages, MPI could accelerate and improve the diagnosis and treatment of neurological disorders. This review provides a basic introduction to MPI, discusses its current use for stroke imaging, and addresses future applications, including the potential for clinical implementation. This article is categorized under: Diagnostic Tools > In Vivo Nanodiagnostics and Imaging Therapeutic Approaches and Drug Discovery > Nanomedicine for Neurological Disease.
AB - Stroke is one of the leading worldwide causes of death and sustained disability. Rapid and accurate assessment of cerebral perfusion is essential to diagnose and successfully treat stroke patients. Magnetic particle imaging (MPI) is a new technology with the potential to overcome some limitations of established imaging modalities. It is an innovative and radiation-free imaging technique with high sensitivity, specificity, and superior temporal resolution. MPI enables imaging and diagnosis of stroke and other neurological pathologies such as hemorrhage, tumors, and inflammatory processes. MPI scanners also offer the potential for targeted therapies of these diseases. Due to lower field requirements, MPI scanners can be designed as resistive magnets and employed as mobile devices for bedside imaging. With these advantages, MPI could accelerate and improve the diagnosis and treatment of neurological disorders. This review provides a basic introduction to MPI, discusses its current use for stroke imaging, and addresses future applications, including the potential for clinical implementation. This article is categorized under: Diagnostic Tools > In Vivo Nanodiagnostics and Imaging Therapeutic Approaches and Drug Discovery > Nanomedicine for Neurological Disease.
U2 - 10.1002/wnan.1757
DO - 10.1002/wnan.1757
M3 - SCORING: Review article
C2 - 34617413
VL - 14
JO - WIRES NANOMED NANOBI
JF - WIRES NANOMED NANOBI
SN - 1939-5116
IS - 1
M1 - e1757
ER -
